Ferini-Strambi points out that for patients with Behçet’s syndrome, cognitive decline in old age may be underrecognized, missed among other age-related changes, or mistaken for “ordinary” dementia. The intersection of chronic inflammation and vascular compromise with traditional neurodegeneration mechanisms suggests that care for these patients demands extra vigilance—and that our biomarkers may need differentiation strategies to avoid false attributions.
Chronic Inflammation and Vascular Insufficiency in Behçet’s Syndrome—A Blindspot in Late-Life Cognitive Decline?
Does Behçet's syndrome, best known for early adult multisystem inflammation, create a hidden burden of late-life cognitive decline through vascular and inflammatory processes?